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Regarding endocrine disruption, common flavonoids such as genistein, quercetin, and apigenin have been reported to activate estrogen receptor signaling pathways at low concentrations, thereby exhibiting phytoestrogen-like activity (Zhang and Wu, 2022)

In its response [15], the ACOG concluded that available studies show no clear evidence that proves a direct relationship between the prudent use of APAP during any trimester and fetal developmental issues. The ACOG further concluded that physicians should not change clinical practice until definitive prospective research is done. Considering the ACOG response, it is important to note that evidence of APAP inducing neurodevelopmental problems during the prenatal period is concerning but limited [2,16,17]

Due to the decentralized and secure nature of the blockchain, it is possible to manage food safety issues, enabling real-time and accurate traceability of food products

10.1016/j.ymgme.2016.03.008 Mol Genet Metab
