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Endo-lysosomal pathway and ubiquitin-proteasome system dysfunction in Alzheimer's disease pathogenesis
Mechanistically, the transcription factor EB (Tfeb) is activated in both early and late stage autosis-related autophagic flux, and the inhibition of late autophagy is mainly mediated by Rubicon [74, 75]
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doi: 10.1038/s41419-020-2442-z 57 LiJPanCBoeseACKangJUmanoADMaglioccaKRet al
