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Description
These compounds include pyruvate, which can be converted into acetyl-CoA and enter the tricarboxylic acid (TCA) cycle or be used for fatty acid synthesis, and -ketoglutarate, a precursor of glutamate and an intermediate of the TCA cycle

The biological effects of such high-dose-rate therapy are known as FLASH 7,8,9,10 : toxic side effects are minimized while ensuring tumor suppression

[DOI] [PubMed] [Google Scholar] 171.Krishna V, Mindel J, Sammartino F, Block C, Dwivedi AK, Van Gompel JJ, Fountain N, Fisher R
Lapatinib is an anticancer medication with low molecular weight and lipophilic characteristics that allow it to pass through the bloodbrain barrier (BBB) [9,10]