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Systemic bacterial invasion induced by sleep deprivation

Knockdown of NNMT in adipocytes was associated with increased NAD+ levels and altered expression of genes involved in energy expenditure, providing the rationale for pharmacological NNMT inhibition [2]

Benefits: *decrease depression *increase brain health *decrease anemia *decrease PMS symptoms Risks when deficient: *increase peripheral neuropathy *increase depression *increase confusion *increase seizures Why Biotin Matters

The comparison isn't straightforward
