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For example, the EP2, EP4, IP, and DP1 receptors activate adenylyl cyclase via Gs, to increase intracellular cAMP whereas EP1 and FP activation couples to phosphatidylinositol metabolism via Gq, leading to the formation of inositol trisphosphate with mobilization of intracellular free calcium

To address the root cause and develop an effective treatment plan, a functional medicine approach often incorporates additional testing to provide a more comprehensive picture of the individual's health

Gastroenterol Res Pract 2020:8024171 Kuzawa CW, Chugani HT, Grossman LI, Lipovich L, Muzik O, Hof PR et al (2014) Metabolic costs and evolutionary implications of human brain development

JCI Insight 3 , e97957 (2018)