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doi: 10.1016/j.intimp.2018.12.030 20 FruhbeckGCatalanVRodriguezARamirezBBecerrilSSalvadorJet al

The reduction in alveolar ventilation could not be attributed to mechanical restriction of lung function, and was unrelated to whether or not the patient was being treated with dopaminergic drugs.

[118] The S -(+) and R -() stereoisomers of ketamine bind to the dizocilpine site of the NMDA receptor with different affinities, the former showing approximately 3- to 4-fold greater affinity for the receptor than the latter

This resulted in 2 to 3-fold higher concentration of the REW-containing variants in plasma over time (Fig