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That's the typical pathway for this demographic: topical exposure first, then discovery of systemic protocols, then a clinical consultation to make sense of the gap between the two

[DOI] [PubMed] [Google Scholar] 98.Theofilopoulos AN, Dixon FJ

It is capable of acting on different protective and common pathways that are generally altered in many cancers, as well as attenuating/inhibiting all stages of carcinogenesis through the inhibition of inflammation, oxidative stress, and proliferation of cancer cells, in addition to the activation of tightly regulated mechanisms of cell death [44,45,46]

Mol Cryst Liq Cryst 580:5257 [Google Scholar] Mortensen A, Skibsted LH (1997) Importance of carotenoid structure in radical scavenging reactions