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Firstly, it decreases the biosynthesis of essential vitamins like thiamine and folic acid, which may contribute to observed vitamin deficiencies [154156]

Although these studies provide a rationale for anthocyanins as a natural drug for potential antimetabolic syndrome, future studies should investigate the potential benefits and optimal dosing of anthocyanins in clinical applications (Table 2)

Due to tolerance development, the side effects caused by this medication and some of its appetite suppressant effects lessen over time, which is one common component of a potentially addictive drug

In a double-blind randomised controlled study, the FM patients were treated either with pregabalin plus CoQ10 or pregabalin plus a placebo for 6 weeks