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(2015) examined age-related gene expression modifications across several organs
By screening in four different media conditions, we uncovered their metabolic regulation, including the fitness defects in the mitochondrial folate transporter SLC25A32 KO cells that can be buffered in galactose condition due to substrate limitation in de novo purine biosynthesis

doi: 10.1016/j.mib.2013.06.003 65 NandaN.BobbyZ.HamideA

Excess iron content was detected in lysosomes of proximal tubule epithelial cells, which could induce renal dysfunction in DKD patients and mice[80]
