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Moreover, lutein can act as a pro-oxidant under tumor conditions: in gastric cancer cells, lutein elevated intracellular ROS via NADPH oxidase, which unexpectedly led to NF-Bmediated upregulation of pro-apoptotic factors and caspase-3 activation, culminating in apoptosis (46)
Most smart protocols begin at 1 mg and only increase if the patient tolerates it well and shows positive response
doi: 10.1007/s11033-021-06444-4 239
In contrast, B12 injections offer a much more direct and reliable solution
