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Research has identified some genetic mechanisms that might result in the development of drug resistance against targeted therapies, which may include secondary mutations, either upstream or downstream of effector activation, and could result in the bypass of certain biological pathways, in addition to epigenetic changes ( Figure 4 )

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Molecular dynamics simulation techniques as tools in drug discovery and pharmacology: a focus on allosteric drugs

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Minamino, M

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When distributed as a reference material, BPC-157 should be clearly and precisely labeled

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