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This principle is the fundamental reason why loading doses are necessary for drugs with very long half-lives such as for amiodarone with a t 1/2 of over 50 days

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1), the results of which we have described below

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As well as acting as a preventative measure, we now know that supplementation with glutathione can help patients infected with the virus and Glutathione has also shown some efficacy in the treatment of those who have a current COVID-19 infection (3)

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doi: 10.18632/oncotarget.3907

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