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Safety, Tolerability, and Regulatory Perspective Multiple non-clinical toxicology programs and clinical studies have evaluated the safety of AOD 9604: A comprehensive non-clinical dossier reported no evidence of genotoxicity or major toxicological concerns across a range of pharmacokinetic and toxicity studies, supporting a favorable safety profile in standard preclinical models

Vitamin B12 is associated with lowering the levels of homocysteine, an amino acid that is associated with cardiovascular disease

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It is widely available through licensed pharmaceutical suppliers and is the diluent most commonly specified in UK trial protocols and compounding guidance from the Specialist Pharmacy Service (SPS)