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[DOI] [PubMed] [Google Scholar] 43.Bolduc J.A., Collins J.A., Loeser R.F
Sorafenib-induced hepatocellular carcinoma cell death depends on reactive oxygen species production in vitro and in vivo
For severe symptoms, like high fevers and intense pain, I often give doses one hour apart
With the exception of C159S and Y296A, this event is very rapid with estimated observed rate constants of 1000 s s 1 , and for this reason a large portion of the flavin reduction phase is generally obscured in the deadtime of the stopped-flow instrument
