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Introduction The concept of the leaky gut also known as increased intestinal permeability has been described many years ago and is currently receiving increasing attention in the scientific literature but also in the media because of its proposed associations with numerous conditions that do not necessarily affect the gastrointestinal (GI) tract, such as asthma, Alzheimer's disease, diabetes among others

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These data indicate that CDKL5 plays a key role for HDAC4 to travel between the cytoplasm and the nucleus