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Next, the centrifugation of the obtained supernatant at 100,000 g for 1 hour allowed the isolation of the ER (pellet) and the cytosolic fraction (supernatant)

doi: 10.1016/s0168-8278(98)80285-7 11

The liver plays a central role in the homeostasis of SAMe through both its synthesis and degradation [2]

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