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As noted above, the mid-region residues (S19 Cagri- P25 Cagri ) form the prototypical bypass motif that was observed for rAmy/San385, constrained by conserved intramolecular hydrogen bonds between the backbone of L16 Cagri /F23 Cagri and S20 Cagri , and the backbone of P25 Cagri and N21 Cagri (Fig

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Evans blue concentration was determined by spectrophotometric measurement at 620 nm and expressed as g/g gingivomucosal tissue as described earlier by our group (6)

NAFLD has become increasingly prevalent in the UK, affecting approximately one in three adults in its early stages, often associated with obesity, type 2 diabetes, and metabolic syndrome