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With the limited amount of high-level evidence, such as provided by systematic reviews and meta-analyses, we could only conclude that the considerations of whether to take supplementation varied by the individuals metabolic status and their nutrient reserves, which span across the continuum of metabolic triage processes that lead to chronic health issues

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This once obscure illness, often hidden in the shadows of more common ailments, silently undermines the lives of many, impacting their vitality and daily routine

Worth mentioning, as Selyes stress concept (Selyes stress response against various noxious agents to reestablish homeostasis) [31,32] gave birth years later to Roberts cytoprotection concept [16,17] (for review see, i.e., [33]), the cytoprotection concept holds a response that is specifically related to prevent or recover damage as such