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L-carnitine and PPAR-agonist Fenofibrate are involved in the regulation of carnitine acetyltransferase (CrAT) mRNA levels in murine liver cells

Klieverik LP, Sauerwein HP, Ackermans MT, Boelen A, Kalsbeek A, Fliers E
168 From the evidence, one can conclude that protein hypersuccinylaiton promotes hypertrophic cardiomyopathy, while there is a decrease of protein succinylation in the ischemic failure heart
In HepG2 cells, L-carnitine reduced free fatty acid-induced apoptosis (72), while similar anti-apoptotic effects occurred in oleic acid-treated hepatocytes (77)