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To evaluate whether group differences in histological outcomes remained significant when accounting for subject- or animal-level variability, we reanalyzed all relevant datasets using linear mixed-effects models

doi: 10.1038/nrc.2016.71 3 PanMReidMALowmanXHKulkarniRPTranTQLiuXet al

Furthermore, the expression of mitochondria-specific markers ( PGC1 , AMPK , SIRT1 , and cytochrome b , etc.) and the protein levels of OXPHOS complexes (complexes I, II, III, IV, and V) in osteocytes are not significantly different between GHRKO and control mice (Liu et al., 2019)
JAMA 325 , 765779 (2021)
