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Advances in fluid-based biomarkers (A, tau, neurofilament light chain), functional neuroimaging (PET, MRI), and genetic profiling (APOE status, transcriptomics) are enabling earlier diagnosis and more personalized treatment strategies
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Therefore, only rats that were unresponsive lost their righting reflex and whose pupils were dilated during ischemia were selected to evaluate completed cerebral ischemia, as recommended by Pulsinelli (Pulsinelli et al
