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Furthermore, another study showed that serum IGF-1 levels, but not PSA levels, tended to be lower in patients with higher surgical Gleason scores

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The schematic representations refer to the inhibitors that belong to: a-d) Kunitz family (BPTI-type), e-i) Kazal family (PSTI-type), j) inhibitor from Streptomyces, k) Kunitz-type family from soybean, l) Bowman-Birk family, m) potato type I family, n) potato type II family Cysteine residues in homologous proteins (those of common ancestry) are very conservative according to PAM 250 scoring matrix (Fig 4)

[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Thapar A., Cooper M