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Description
This phenomenon may occur in the lymphocytes during the development of an immune response or also in muscular cells during strenuous exercise
Ovarian cancer-associated antigen 66 (OVA66) was first shown to play a role in ovarian cancer by reducing IGF-1R expression and downstream phosphorylation of ERK1/2-Hsp27 signaling

The two pathways collaborate to complete autophagosome maturation (31)

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