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Marked thrombosis, arterial and venous, peripherally and centrally, occur as prominent stasis and vessel failure progress (i.e., congested inferior caval vein and superior mesenteric vein, failed azygos vein unable to serve as a rescuing pathway with direct delivery to the superior caval vein [14,15,16,17,18,19,20,21,22,23])

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Pre-existing conditions: Generally safe even with most health conditions since it doesn't affect blood sugar, blood pressure, or hormone levels