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39 In addition, the reactive aldehydes such as acrolein and 4-hydroxy-2-nonenal (4-HNE) formed from lipid peroxidation cause damage to the epithelial cells, acrolein is unstable and toxic, whereas 4-HNE in high concentrations is capable of inducing caspase (a major promoter of cell apoptosis)
As with any medical treatment, it's important to weigh the potential benefits against possible side effects and costs
In our view, the removal alone should not be understood as a new FDA determination of eligibility
Liver and spleen weights were expressed as a percent of the total body weight (for normal rats, liver 3.2%4.0% and spleen 0.20%0.26%)
