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doi: 10.1097/MCP.0000000000000210
Microglia cells can have two phenotypes: the proinflammatory classic M1 phenotype, which is associated with anti-inflammatory cytokine production, antigen-presenting properties, and ROS production, and the M2 anti-inflammatory alternative phenotype possessing anti-inflammatory and immunoregulatory activity [253]
Methyl-B12 treatment balanced the high CD4/CD8 T cell count and increased NK cell activity, increasing immunity [21]
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