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Rather, sleep apnea patients exhibited increased TNF concentrations in the afternoon, the time period during which concentrations in normal control subjects are at a minimum

Functional outcomes also improved with the combination treatment

doi: 10.1016/j.neuropharm.2007.03.016 226 ZoggH.SinghR.HaS

Current treatment options include approved drugs such as serotonin-norepinephrine reuptake inhibitors, e.g., duloxetine, gabapentinoids such as pregabalin and gabapentin, topical treatment with capsaicin, and several off-label use drugs such as other antidepressants (e.g., tricyclic antidepressants), antiepileptic drugs, and weak and strong opioids