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Knee Osteoarthritis Injection Choices: Platelet- Rich Plasma (PRP) Versus Hyaluronic Acid (A one-year randomized clinical trial)

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In CuCP complex, which constitutes approximately 75% from the total copper pool (our data and 4,5 ), the copper ions are bound in protein interior, which makes them kinetically inert and practically nonexchangeable at physiological pH values even in the presence of high millimolar concentrations of powerful Cu(II)-chelating ligands like EDTA or DTPA