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(2023) Foslevodopa-Foscarbidopa (Vyalev): CADTH Reimbursement Recommendation: Indication: For the treatment of motor fluctuations in patients with advanced levodopa-responsive Parkinsons disease who do not have satisfactory control of severe, debilitating motor fluctuations and hyper-/dyskinesia despite optimized treatment with available combinations of Parkinsons medicinal products

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After an initial loading regimen of 1mg three times weekly for two weeks, maintenance therapy is typically 1mg every three months for life in conditions like pernicious anaemia, or every two months if neurological involvement was present