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However, with the recognition of apoptosis and its detailed signaling mechanisms, reports were published suggesting that APAP also triggers apoptotic cell death [40, 41]

Previous studies have shown that a small molecule called Ras Lethal 3 ((1S,3R)-RSL3,(RSL3)) can pharmacologically inhibit GPX4 in skin and soft tissue cancer models in vitro and leads to induction of ferroptosis 10,11

Instead, ABHD11 inhibition and impaired OGDHc function alter fatty acid metabolism and CD8 + T cell differentiation, increasing the central memory T cell (T CM ) pool

Various antioxidants, such as vitamin E and resveratrol, have been studied for their hepatoprotective properties [69,70]