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Furthermore, three cases of severe hepatobiliary disease were recently documented in patients with X-linked myotubular myopathy (XLMTM), who received a high dose (3 10 14 genome copies/kg) of AAV8 expressing the therapeutic MTM1 gene [118]

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In one study on the Shank3-deficient ASD mouse model, the chronic administration of OXT prevented social deficits after 2 weeks of treatment but led to social ambivalence beyond that

Certain side effects have been reported in clinical trials, including gastrointestinal discomfort and allergic reactions