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Description
As a selenoprotein, GPX4 is the main catalytic enzyme that mediates PLOOH reduction and detoxification in mammalian cells
Proteomic analysis Cells were seeded in 10-cm dishes and cultured for 7 days in cystine-free medium supplemented with heavy isotope-labelled 13 C 6 , 15 N 2 -cystine (Cambridge Isotope Laboratories, CNLM-4244-H)
We want facts and figures
Only a fraction of these vast waters has been explored, and much of the underwater world is little understood
