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The reason for occurring this phenomenon (reduction of CySGly- but not of GS-bound Mercury(II)) in solution and in the biological environment of cells is reasonably a consequence of the low reducing electrochemical potential of CySGly (at 0.282 V the most reducing one of the whole soluble physiological thiolome)

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All together, these results demonstrate that protective immunity against Wuhan strain (B lineage) and Delta variant is primarily mediated by nAbs, whereas protection in immunized mice against Gamma seems to be mediated by both nAbs and T cells