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With prolonged exposure to continuous progesterone as with long-term injectable preparations of Medroxyprogesterone, the womb lining gets soggy or spongy (decidualized) and is highly unfavorable to the implantation of any pregnancy, wherefrom comes the contraceptive benefit of such a depot formulation

Gel capsules suitable for use in preparing SAG compositions discloses herein should protect ingredients from full disintegration in the stomach and target capsule disintegration for the small intestine

Lerman TT, Cohen E, Sochat T, Goldberg E, Goldberg I, Krause I

[DOI] [PubMed] [Google Scholar] Torres-Lugo M, Garcia M, Record R, Peppas NA