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Target proteins include a wide range of enzymes with active site or regulatory SH groups, such as glyceraldehyde-3-phosphate dehydrogenase in glycolysis and protein kinases in signaling cascades, as well as chaperones and transport proteins
The condition may happen both during the day and night and may interfere with sleep
We further assessed its potential in a series of cellular assays where GPX4 was demonstrated to play a regulatory role
