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INFLUENCE OF HCC TUMOR CELL METABOLIC REPROGRAMMING ON THE TME The TME of HCC is a highly organized and metabolically dynamic ecosystem composed of immune cells, stromal components - including cancer-associated fibroblasts (CAFs) and endothelial cells - extracellular matrix (ECM), and locally enriched signaling molecules

The following paragraphs will revisit our previous knowledge on the effect of various circulating molecules on RBC deformability and integrate our new knowledge regarding eryptosis

The cellular balance of glutathione is regulated via several enzymes, one of which is glutathione peroxidase

[DOI] [PMC free article] [PubMed] [Google Scholar] 51.Horvath S.E., Daum G