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These hits exhibited strong homology to the LldD superfamily (FMN-dependent -hydroxy acid oxidases), with E-values ranging from 1 10 - to 6 10 - and sequence coverage between 28.53% and 48.51%

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Recent studies have identified that spd_16421643 gene from Streptococcus pneumoniae encodes the ABC transporter EgtU, which exhibits high affinity and specificity for ERG [109]

Since kidney function is reduced during AKI, activation of the urea cycle and subsequent urea generation together lead to a substantial rise in BUN 14,35
