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It is characterized by microglial activation and enhanced release of inflammatory factors, such as tumor necrosis factor (TNF-), IL-2, IL-10, IL-4, IL-6, and interferon , which contribute to neuronal injury and death [30, 31]
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Ideally, it should be taken on an empty stomach

these pathways enhance the efficacy of chemotherapy/radiotherapy and improve treatment outcomes in vivo (13, 14)
