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Schroder TH, Sinclair G, Mattman A, Jung B, Barr SI, Vallance HD, et al

Blocks NNMT in fat cells In 3T3-L1 mouse fat cells, 30 M of 5-Amino-1MQ for 24 hours strongly lowered 1-MNA levels direct proof of NNMT inhibition (Neelakantan et al., Biochemical Pharmacology, 2018)

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People may develop dementia in the final stage (Selhub et al., 2008)