glutathione complexed fe-s centers Regulatory networks of iron sulfur cluster biology in cancer mechanisms and therapeutic perspectives: iScience Glutathione-driven redox decisions in cell
Description
Liver fibrosis is a key marker of MASLD/MASH progression, initiated by elevated hepatocyte expression of pro-fibrotic TFs such as Sox9 and secreted factors such as Spp1 (osteopontin) and Tgfb1 (TGF-1)
EDIT: Your post intrigued me and I was a bit concerned about the assumption that normal ferritin levels meant that haemochromotosis is not present
C Kelnar, Edinburgh
Melatonin ameliorates hepatic ferroptosis in NAFLD by inhibiting ER stress via the MT2/cAMP/PKA/IRE1 signaling pathway
