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The IL-8 signaling pathway is involved in neuroinflammation, resulting in progressive neural sensitization in OIPN model [82]
Furthermore, some newer agents for metastatic hormone-sensitive PCa may require more extensive preclinical testing in multiple models and need to demonstrate better synergistic effects with standard-of-care agents before introduction into clinical trials

This isnt to say the glutathione itself is harmful

Oral bioavailability is low commonly cited around 610%, largely due to first-pass metabolism
