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Description
Realistic skin improvements begin appearing around week 4-6 as the first collagen remodeling cycle completes and continues improving through week 12 and beyond

On day 0 of adulthood as indexed in the figure legend, ~5060 L4/YA worms per plate (unless otherwise noted) were transferred onto fresh NGM or RNAi plates
Other common foods (both animal and plant) also provide small amounts of analogues that do not cause problems

The magnitude of weight loss was dose-dependent, with the 2.4 mg dose showing a clinically meaningful reduction
