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In addition to -TRCP, a number of additional mechanisms, posttranslational modifications, and cross talk with other signaling pathways have been proposed to play a role in the regulation of NRF2s activity (Table 4)

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Dietary nutrients derived from plants have been linked to acting as active ingredients in some herbal and traditional medications ( Ginger, Sesamum indicum , has natural antioxidants that greatly reduce lipid peroxidation and heavy metal toxicity (72, 73)

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Cysteine and cystine are two interconvertible forms of a sulfur-containing amino acid

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