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Furthermore, in animal models, glycyrrhizin has been shown to inhibit the activation of hepatic stellate cells (HSCs) and induce their apoptosis by blocking NF-B nuclear translocation, thereby preventing liver fibrosis ( 3.1.2 Interference with arachidonic acid cascade In an lipopolysaccharide (LPS)-stimulated macrophage model, researchers found that MgIG inhibited the activation of PLA 2 in LPS-stimulated macrophages ( 2 (PLA 2 ) is the key initiating enzyme of the arachidonic acid cascade, responsible for catalyzing the hydrolysis of membrane phospholipids to release arachidonic acid
Different data provided by Aras et al

Instead of destroying the molecule, these enzymes remove the phenylacetyl group and release active glutathione directly into your cells

E., Vieira, P., Rodrigues, N
