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Gillis RA et al (1985): Mechanism of the Antihypertensive Effect of Alpha2-Agonists

Kayacan, Y., etinkaya, A., Yazar, H

A bound KEAP1:NRF2 complex is inactive until it engages two molecules of CUL3 to create a CUL3:KEAP1:NRF2 complex at a 2:2:1 stoichiometry
