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METH-induced neurotoxic effects include damage to dopaminergic and serotonergic terminals, neuronal apoptosis, as well as activated astroglia and microglia that lead to a neuroinflammatory response within the brain (Cadet and Krasnova, 2009

Day 61 or thereafter if : If no additional glycemic control is needed, then maintain the dosage at 4 mg orally once daily

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After introducing the lubricated transducer into the rectum, it was slowly rotated 90 clockwise and 180 anticlockwise to image the entire reproductive tract by B-mode ultrasonography