neuronal glutathione synthesis in vivo Brain Disorders and Aging Glutathione Metabolism of the Brain—The

A number of extracellular antioxidant proteins have been described to localize to the ECM of the lung, suggesting a potential protective role in presence of oxidative stress 31 , in particular, glutathione peroxidase 3 (GPX3) and extracellular superoxide dismutase (EC-SOD or SOD3) 26,27,28,32,33

Moreover, GBM has a high metabolic rate, which results in increased basal levels of ROS and the generation of an immunosuppressive tumor environment

Jones GD, Droz B, Greve P, et al

The production of high-quality GO remains complicated, involving toxic reagents, high temperatures, and expensive processes that hinder large-scale, defect-free, and environmentally sustainable production 174