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Acknowledgements We would like to thank Bruce Wolffenbuttel and Andrew McCaddon for their advice and assistance of this perspective

Congenital IGF-1 deficiency may result from GH gene deletion, GH releasing hormone (GHRH) receptor defects and IGF-1 resistance

[22] Each 1 mL of Lipo-B injection typically contains approximately 25 mg of methionine, 50 mg of choline chloride, and 1 mg of cyanocobalamin (vitamin B), provided in multi-dose vials by compounding pharmacies

Compounded medications are not FDA-approved as finished drugs
