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The effects of Mg deficiency on circadian clock genes expression might be due to impaired sugar production or partitioning, and sugar plays some roles in circadian entrainment [106]
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In addition, mouse BMECs were also found to produce inflammatory responses upon LPS stimulation, specifically by directly producing inflammatory factors such as interleukin (IL)-1, IL-18, IL-6, and TNF-, and these factors are able to mediate the damaging effects of LPS on the BBB (Smyth et al., 2018

It seems that it has rarely been tested if the increase (or maintenance) of GSH levels is actually required for the rescuing effect afforded by NAC
