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The renin-angiotensin system (RAS) comprises the classic arms, which include the angiotensin (Ang) II/angiotensin-converting enzyme (ACE)/Ang II type 1 receptor (AT 1 R) axis associated with blood pressure elevation and organ damage, and the protective arms, involving Ang (1-7)/ACE2/Mas axis, which offers organ-protective effects [2]
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